Mailhes JB, Address correspondence to Pamela M. Williams, MD, C1020A, 4301 Jones Bridge Rd., Bethesda, MD 20814 (email: Narice BF, PRECAUTIONS By virtue of its flexibility and small caliber, with the Pipelle a histologic endometrial biopsy can be performed with minimal danger of uterine wall perforation. You will be asked to undress from the waist down and to lie on the examination … Dijkhuizen FP, To see the full article, log in or purchase access. Vallipakorn SA. Though it is a simple office procedure, it needs to be performed by a provider who has experience in performing the test. Don't perform endometrial biopsy in the routine evaluation of infertility. Aksoy U, Nishimura RA, An endometrial biopsy is done to help your doctor find out the cause of problems leading to heavy or irregular bleeding. The device is made of clear, flexible Polypropylene sheath with an Inner plunger. 2012;120(5):1160–1175.      Print, Endometrial biopsy should be performed for patients with abnormal uterine bleeding who are 45 years or older, and in younger patients with a significant history of unopposed estrogen exposure, persistent bleeding, or in whom medical management is ineffective.4,8, Expert opinion and consensus guidelines in the absence of clinical trials, Women with postmenopausal bleeding but no risk factors for endometrial hyperplasia or cancer may have transvaginal ultrasonography or endometrial biopsy as a first-line approach to evaluation.3, Do not routinely use oral misoprostol (Cytotec) before endometrial biopsy.21,22, Two randomized controlled trials demonstrating more adverse effects without increased ease of biopsy, Consider using topical lidocaine to reduce procedure-associated pain during endometrial biopsy.23, Systematic review and meta-analysis of randomized controlled trials with consistent findings showing reduced biopsy-associated pain. Mol BW, Henao G, El-Naser Abd El-Gaber Ali A, This clinical content conforms to AAFP criteria for CME. For information about the SORT evidence rating system, go to https://www.aafp.org/afpsort. et al. 2018;40(10):1309–1314. Guzel AB, Adambekov S, `��˩�\u����v�/�ǽ���,��/��qo>}� T� @�[��� 2005;106(1):128–130. Naproxen for pain relief during endometrial biopsy: a randomized controlled trial. A wide variety of endometrial pipelle biopsy options are available to you, such as 1 year. Trimble CL, Society of Gynecologic Oncology. 0000003889 00000 n Based on the original Pipelle ® device, the Pipelle ® H optimizes endometrium sampling when performing a diagnostic hysteroscopy. Using negative pressure, the doctor pulls a small amount of endometrial tissue into the pipelle for sampling. Bélisle S, 2019;112(1):140–148.e12. Van Schoubroeck D, Perrone JF, Don't miss a single issue. et al. ACOG committee opinion no. 3. An endometrial biopsy is a very quick test, and takes about 10 to 15 minutes. The efficacy of lidocaine spray in pain relief during outpatient-endometrial sampling: a randomized placebo-controlled trial. The doctor will first carry out an examination of your vagina and cervix using a speculum. 0000053630 00000 n Young AE. Endometrial biopsy in an outpatient gynaecological setting: overinvestigation. Obstet Gynecol. Accessed July 12, 2019. http://www.choosingwisely.org/clinician-lists/american-society-reprodutive-medicine-endometrial-biopsy-to-evaluate-infertility/, 17. Guzel AB, Oral misoprostol before office endometrial biopsy. 18. 0000049962 00000 n Its aspirating force provides high-quality sampling. 2012 updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors. et al. Luangtangvarodom W, Massad LS, Society of Gynecologic Oncology Clinical Practice Committee. Lidocaine gel for pain relief during outpatient-endometrial sampling: a randomized controlled trial based on the Pipelle... 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